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KMID : 1007519960050040334
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Food Science and Biotechnology
1996 Volume.5 No. 4 p.334 ~ p.337
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Screening of Angiotensin I - Converting Enzyme Inhibitors in Cereals and Legumes
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Rhyu, Mee Ra
Nam, Young Joong/Lee, Hyun Yu
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Abstract
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Angiotensin I-converting enzyme (ACE) inhibitory activities were investigated in the fractions of crude extracts, dialysates and peptic hydrolyzates of 20 kinds of cereals, legumes, sesame and perillar seeds. In the fraction of crude extracts, ACE inhibitory activities were not detected in cereals, legumes, sesame and perillar seeds except in buckwheat. The ACE inhibitory activity of buckwheat disappeared upon dialysis. Dialysates from all samples tested did not show ACE inhibitory activities. However, all sample fractions of peptic hydrolyzates showed ACE inhibitory activities, and these activities increased upon concentration of sample. Generally, legumes that contained higher quantity of proteins produced higher levels of peptides by peptic digestion, and legumes showed higher ACE inhibitory activities than cereals. But the quantities of substrate proteins and digested peptides did not always correlate with the amount of ACE inhibitory activities. These results suggested that the production of ACE inhibitory peptides would be affected by not only the quantities of substrate proteins but also the types of substrate proteins. We conclude that the ACE inhibitory activity is detected in all peptic hydrolyzates assayed in this study, and that most food containing protein would produce ACE inhibitory activities through the intestinal digestion of human beings, although the amounts of activities would vary in different varieties of foodstuffs.
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